Significance of Cephalin-cholesterol Flocculation Test
نویسندگان
چکیده
The effect of malarial fever on hepatic physiology has recently been investigated. It has been found (1) that considerable bromsulphthalein retention, a marked reduction in cholesterol and cholesterol esters, a moderate fall in phospholipids, diminished hippuric acid excretion and a strongly positive cephalin-cholesterol flocculation reaction resulted when malaria was induced in 9 patients by inoculation with Plasmodium vivax for the treatment of central nervous system syphilis. Other investigators (2) studied 10 patients with acquired malaria in all of whom the cephalincholesterol reaction was positive. The aforementioned authors (3) noted a hypoproteinemia with a decrease in serum albumin and an increase in globulin in patients with therapeutic malarial fever. In this communication, data are presented dealing with changes in the various serum protein fractions occurring during malarial fever, and correlating these findings with the cephalincholesterol flocculation test.
منابع مشابه
Improved Quantitation of Cephalin-cholesterol Flocculation Test.
A rapid turbidimetric method for the determination of cephalin-cholesterol flocculation is described. Greater specificity and photometric sensitivity have been achieved along with adequate precision. The test is standardized with the conventionalbarium sulfate turbidity standards usedfor other laboratory procedures. Definition of results in turbidity units is proposed, and photometric standardi...
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